Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
A Dynamic Hybrid Weighting Framework for Teaching Effectiveness Evaluation in Multi-Criteria Decision-Making: Integrating Interval-Valued Intuitionistic Fuzzy AHP and Entropy Triggering. [PDF]
Entropy (Basel)Lu C, Zhang Y.
europepmc +1 more source
An Integrated Engineering Model Based on the Object-Oriented Framework for Plant Control Systems
, 2001 Hideyuki Takada, Akira Sugimoto
openalex +2 more sources
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Tunable Plug-and-Play Meta-Nanogenerator Materials for Multi-Range Force Measurements. [PDF]
Adv Sci (Weinh)Premadasa R +6 more
europepmc +1 more source
An Evaluation Method for Model Maturity Supporting Model-Based Systems Engineering at the Conceptual Design Stage [PDF]
Chong Jiang, Wu Zhao, Tong Li, Jun Li
openalex +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Production System Monitoring Based on Petri Nets Enhanced with Multi-Source Information. [PDF]
Sensors (Basel)Liu P +5 more
europepmc +1 more source
Application of Model-based Systems Engineering
, 2009 The Objective of this Project was to Develop a System Engineering (SE) Methodology for Creating Complex, Supportable System Architectures that: – Utilize a Model Based Systems Engineering (MBSE) approach – Integrate Requirements Traceability – Implement Open Architecture (OA) and SPLs – Identify a structure which supports Combat System Software Reuse –
openaire +1 more source