Results 21 to 30 of about 879,678 (198)
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij +11 more
wiley +1 more source
A Framework of Modeling and Simulation Based on Swarm Ontology for Autonomous Unmanned Systems
For the emerging autonomous swarm technology, from the perspective of systems science and Systems Engineering (SE), there must be novel methodologies and elements to aggregate multiple systems into a group, which distinguish the general components with ...
Xinghai Gao +6 more
doaj +1 more source
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro +10 more
wiley +1 more source
A remote maintenance robot system (RMRS) plays a critical role in safeguarding the fusion energy experimental device’s security and stability. State-of-the-art intelligent technology such as cognitive digital twins (CDTs) is widely considered capable of ...
Zhixin Yao +9 more
doaj +1 more source
Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig +13 more
wiley +1 more source
Digital Twin’s Anatomy: A Cross-Sector Framework With Healthcare Validation
Digital twins (DT) in manufacturing, healthcare, and across different industrial domains are often over-simplified as solely a virtual representation of a physical object or service.
Sina Namaki Araghi +4 more
doaj +1 more source
Application of Model-Based Systems Engineering Concepts to Support Mission Engineering
This paper presents an approach to the utilization of model-based systems engineering (MBSE) early in the system lifecycle, which focuses on early identification of desirable system characteristics to support mission engineering (ME). The paper relies on
Paul Beery, Eugene Paulo
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Wind turbines (WT) are complex multidisciplinary systems containing a large number of mechanical, control, and electrical components. Model-Based Systems Engineering (MBSE) provides an approach for cross-discipline development to address the system ...
Yizhe Zhang +4 more
doaj +1 more source

