Results 211 to 220 of about 3,497,010 (299)

Correction: Transdisciplinary model-based systems engineering in the development of the Ruminant Farm Systems model

Frontiers in Sustainability
Haowen Hu, Clifford A. Whitcomb, Thomas E. Ploetz, Kristan F. Reed, Kristan F. Reed   +4 more
doaj   +1 more source

Large Language Model-Based Agents for Physical Activity and Cognitive Training: Scoping Review. [PDF]

JMIR AI
Silacci A, Giachetti B, Angelini L, Lopomo NF, Andreoni G, Mugellini E, Cherubini M, Caon M.   +7 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Deep Learning-Enabled Diabetic Retinopathy Screening: A Techno-Clinical Revolution or Just More Artificial Intelligence Hype? [PDF]

Diabetes Care
Dave D, Steinhubl SR, McQueen RB.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Automated assessment of technological and financial drivers of greenhouse gas reduction in sustainable renewable energy systems. [PDF]

Sci Rep
Chandra S, Abdulhadi AR, Hdeib R, Beemkumar N, Mahapatro A, Jacob A, Al-Hedrewy M, Eshchanov T, Madaminov B.   +8 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Bridging art and AI in the global south: the development of the robot Zequinha considering the grand challenges of human-centered artificial intelligence. [PDF]

Front Robot AI
da Cunha AC, Lira EG, Dansa de Alencar SJ, Bartholo R, Caulliraux HM.   +4 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source