Results 111 to 120 of about 34,600,335 (260)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Testing Goodness-of-Fit of Parametric Models for Censored Data

open access: yes, 2011
A goodness-of-fit test for left-, right- and interval-censored data, assuming random censorship is proposed and studied. In the first step of the test, the null model is extended to a series of nested alternative models for censored data as in Zhang and ...
NYSEN, Ruth, FAES, Christel, AERTS, Marc
core   +1 more source

Leukopoiesis model fit to average patient data.

open access: yes, 2014
Solid dots represent average patient data and curve represent leukocyte model (Eqn. 4) fit. The model mimics the clinical observation during 6-MP treatment; Depletion of leukocytes following 6-MP dosing has been countered by the body's feed-back ...
Ann E. Rundell (196053)   +4 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Psychometric Evaluation of the Assessment of the Burden of COPD Scale According to the Rasch Model

open access: yesCOPD
To facilitate shared decision-making in Chronic obstructive pulmonary disease (COPD), the Assessment of the Burden of COPD (ABC) tool was developed. An integral part of the ABC tool is the ABC scale, a questionnaire to determine COPD burden.
Maarten Voorhaar   +4 more
doaj   +1 more source

Three New Studies on Model-data Fit for Latent Variable Models in Educational Measurement

open access: yes, 2019
This dissertation encompasses three studies on issues of model-data fit methods for latent variable models implemented in modern educational measurement. The first study proposes a new statistic to test the mean-difference of the ability distributions estimated based on the responses of a group of examinees, which can be used to detect aberrant ...
openaire   +2 more sources

Biophysical model fit.

open access: yes, 2019
(A) Histograms show probability distributions of the likelihood of the three biophysical models, given the dataset of genetic parentage assignments. The consistent model (blue) provides the unambiguous best fit to the data.
Severine Choukroun (3344453)   +6 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Multifidelity co-kriging metamodeling based on multivariate data fusion for dynamic fit improvement of injection mechanism in squeeze casting

open access: yesAlexandria Engineering Journal
To improve the dynamic fit the injection mechanism in a squeeze casting machine, this paper proposes a novel multifidelity co-kriging (MFCK) metamodeling method, which fuses high-fidelity measured data with low-fidelity simulated data and considers data ...
Dongdong You   +3 more
doaj   +1 more source

Response Surface Methodology Using a Fullest Balanced Model: A Re-Analysis of a Dataset in the Korean Journal for Food Science of Animal Resources

open access: yesFood Science of Animal Resources, 2017
Response surface methodology (RSM) is a useful set of statistical techniques for modeling and optimizing responses in research studies of food science. In the analysis of response surface data, a second-order polynomial regression model is usually used ...
Sungsue Rheem, Insoo Rheem, Sejong Oh
doaj   +1 more source

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