Results 171 to 180 of about 11,397 (304)

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

MSSA: memory-driven and simplified scaled attention for enhanced image captioning. [PDF]

Sci Rep
Hossain MA, Ye Z, Hossen MB, Rahman MA, Islam MS, Abdullah MI.   +5 more
europepmc   +1 more source

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac, Enver Fehim Koçpinar, Hamid Ceylan   +2 more
wiley   +1 more source

Visible-Infrared Fusion Based on CNN and Deformable Transformer. [PDF]

J Imaging
Wang X, Gu X, Li B, Zhang M, Yang P, Fu Q.   +5 more
europepmc   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan, Musa Tatar, Yener Yazğan, Kıymet Kübra Tüfekci   +3 more
wiley   +1 more source

Chlorfenapyr Induces Hepatotoxicity Associated With Oxidative Stress and Mitochondrial Dysfunction Involving Keap1/Nrf2 Signaling

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorfenapyr (CHL) is a widely used pyrrole insecticide, but its hepatotoxic effects and underlying mechanisms remain incompletely understood. This study investigated the toxic effects of CHL on rat liver and BRL‐3A hepatocytes and explored the involvement of the Keap1/Nrf2 signaling pathway. Rats were administered CHL (10, 20, or 30 mg/kg) by
Dongquan Zhao, Jia Li, Cheng Li, Hua He, Lipu Deng   +4 more
wiley   +1 more source

A translational mechanistic synthesis of ischemia-reperfusion injury in experimental flap models toward free flap salvage. [PDF]

Front Surg
Akdemir O.
europepmc   +1 more source

Redox‐Associated Renal and Male Reproductive Alterations Following Dexamethasone Exposure in Male Rats: Histopathological and Spermatological Evaluations

Journal of Applied Toxicology, EarlyView.
ABSTRACT Dexamethasone (DEX) is widely used in clinical practice, although it may also cause oxidative stress–related damage in different tissues, including the kidney and male reproductive system. This study investigated DEX‐induced renal and reproductive injury in rats and evaluated the modulatory effect of reduced glutathione on DEX‐associated redox
Caner Öztürk, Neşe Hayat Aksoy, Erkan Özkan, Ayşe Ikinci Keleş, Ahmet Karabulut   +4 more
wiley   +1 more source

Convergent death programs in chronic obstructive pulmonary disease: how pyroptotic and ferroptotic crosstalk reshapes therapeutic paradigms. [PDF]

Front Immunol
Huang A, Liu S, Lan J.
europepmc   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, EarlyView.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source