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Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Hybrid AI/ML-mechanistic framework enables intelligent optimization of commercial biopharmaceutical downstream processing. [PDF]

open access: yesMAbs
Wang RZ   +14 more
europepmc   +1 more source

Rising Air-Conditioning Use Intensifies Global Warming. [PDF]

open access: yesNat Commun
Zhang H   +12 more
europepmc   +1 more source

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