Results 51 to 60 of about 952,227 (243)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Model-Driven Development of Web Augmenters for Facilitating Environmental Open Data Consumption
Citizens must consume open data published by public institutions to be aware of environmental issues of SDGs (Sustainable Development Goals). However, the existence of many related heterogeneous open data sets hampers citizens to access and consume them ...
Paula Gonzalez-Martinez +4 more
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A Universal Framework for Skill-Based Cyber-Physical Production Systems
In the vision of smart manufacturing and Industry 4.0, it is vital to automate production processes. There is a significant gap in current practices, where the derivation of production processes from product data still heavily relies on human expertise ...
Max Hossfeld, Andreas Wortmann
doaj +1 more source
The MODAClouds Model-Driven Development [PDF]
The Cloud computing market encompasses an ever-growing number of providers offering a multitude of infrastructure-as-a-service (IaaS) and platform-as-a-service (PaaS) solutions. In order to exploit the peculiarities of each Cloud solution as well as to optimize performances, availability, and cost, an emergent need is to run and manage multi-Cloud ...
Nicolas Ferry +2 more
openaire +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Model-based approach for specifying requirements of virtual reality software products
IntroductionGathering requirements for developing virtual reality (VR) software products is a labor-intensive process. It requires detailed elicitation of scene flow, articles in the scene, action responses, custom behaviors, and timeline of events.
Sai Anirudh Karre, Y. Raghu Reddy
doaj +1 more source
Software Architecture and Framework to Develop NFC-Based Applications
Applications are employing Near Field Communication (NFC) technology to interact with physical objects by using NFC tags. The architecture to implement these kinds of applications varies according to non-functional requirements such as the physical ...
Ricardo Tesoriero, Jose A. Gallud
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source

