Results 71 to 80 of about 1,142,184 (218)
INDIeAuthor: A Metamodel-Based Textual Language for Authoring Educational Courses
IEEE Access, 2019 This paper presents the INDIeAuthor authoring tool, which has been developed at the Digital Content Production Center, Polytechnic University of Cartagena (UPCT).
Daniel Perez-Berenguer +1 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Simulation of Road Traffic Applying Model-Driven Engineering
Advances in Distributed Computing and Artificial Intelligence Journal, 2016 Road traffic is an important phenomenon in modern societies. The study of its different aspects in the multiple scenarios where it happens is relevant for a huge number of problems.
Alberto FERNÁNDEZ-ISABEL +1 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Edge IoT Prototyping Using Model-Driven Representations: A Use Case for Smart Agriculture
SensorsIndustry 4.0 is positioned at the junction of different disciplines, aiming to re-engineer processes and improve effectiveness and efficiency. It is taking over many industries whose traditional practices are being disrupted by advances in technology and
Ivan Guevara +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Scale Modular Test Platform for the Characterization of PD Measuring Systems Using HFCT Sensors
SensorsToday, online partial discharge (PD) measurements are common practice to assess the condition status of dielectrics in high-voltage (HV) electrical grids.
Eduardo Arcones +3 more
doaj +1 more source
Usability evaluation of the domain specific language for spatial simulation scenarios
Cogent Engineering, 2018 This article presents the results of a usability evaluation initiative conducted on the Domain Specific Language for Spatial Simulation Scenarios (short name DSL3S) and its supporting tools.
Luís Moreira de Sousa +1 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source