Results 121 to 130 of about 19,125,334 (286)
A Language for Modeling Declarative Knowledge Bases in the Context of Model-Driven Engineering
ComputersEnd-user development (EUD) and model-driven engineering (MDE) are particularly valuable for building classical intelligent systems that rely on declarative knowledge bases.
Aleksandr Yurin, Nikita Dorodnykh
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Motorola WEAVR: Aspect Orientation
, 2008 This paper presents an Aspect-Oriented Software Development (AOSD) language and methodology for Model-Driven Engineering (MDE) of large distributed applications, and a tool that implements these concepts, the Motorola WEAVR.
Model-driven Engineering
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
DESIGN CHARTS IN N-VISUAL LANGUAGE AND BUSINESS PROCESS MODELING
Вестник Донского государственного технического университета, 2018 Problems that permit solution of charts in N-Visual Language dealing with design and automatic code generation of the software information systems are described. Collecting of design diagrams in N-Visual Language with modeling business processes diagrams
Oleg V. OLKHOVIK
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Model-driven engineering for the social enterprise
, 2022 Model-driven engineering for the social ...
John Grundy (13076748)
core
Advances in Model Driven Software Engineering.
ERCIM News, 2012 Empirical evidence shows that the use of model driven software engineering can result in an up to 10-fold quality improvement and decreased development time. Researchers from Eindhoven University of Technology tested this on a detector control system at CERN. This brings Turing’s vision of software another step closer.
Brand, van den, M.G.J., Groote, J.F.
openaire +2 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source