Results 31 to 40 of about 308,743 (257)

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Waypoint-tracking Control of a Benthic AUV Based on Model-free Adaptive Control Method

open access: yes水下无人系统学报, 2022
In this study, the model-free adaptive control(MFAC) method was applied to a waypoint-tracking control system to solve the problems of high uncertainty in the marine environment and difficulty in accurately determining the benthic autonomous undersea ...
Peng GAO   +4 more
doaj   +1 more source

Speed-Adaptive Model-Free Lateral Control for Automated Cars

open access: yesIFAC-PapersOnLine, 2022
8th Joint IFAC Conference: SSSC-TDS-LPV, September 27-30, 2022 -- Montreal ...
Marcos Moreno-Gonzalez   +4 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Model-free adaptive chaos control for the boost converter

open access: yesMeasurement + Control
In order to solve the dynamic analysis and chaotic motion control problems of the current-mode-controlled Boost converter system, a state equation model in the continuous current mode is established.
Ning-zhou Li   +2 more
doaj   +1 more source

Data-Driven Model-Free Adaptive Control Based on Error Minimized Regularized Online Sequential Extreme Learning Machine

open access: yesEnergies, 2019
Model-free adaptive control (MFAC) builds a virtual equivalent dynamic linearized model by using a dynamic linearization technique. The virtual equivalent dynamic linearized model contains some time-varying parameters, time-varying parameters usually ...
Xiaofei Zhang, Hongbin Ma
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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