Results 151 to 160 of about 343,435 (310)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Model Uncertainty and Policy Evaluation: Some Theory and Empirics [PDF]
This paper explores ways to integrate model uncertainty into policy evaluation. We first describe a general framework for the incorporation of model uncertainty into standard econometric calculations.
Steven N. Durlauf +2 more
core
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Growth, Convergence and Public Investment. A Bayesian Model Averaging Approach
The aim of this paper is twofold. First, we study the determinants of economic growth among a wide set of potential variables for the Spanish provinces (NUTS3).
Roberto Leon Gonzalez +1 more
core
Imposing parsimony in cross-country growth regressions [PDF]
The number of variables related to long-run economic growth is large compared with the number of countries. Bayesian model averaging is often used to impose parsimony in the cross-country growth regression.
Jarociński, Marek
core
Bayesian multiregional clinical trials using model averaging. [PDF]
Biostatistics, 2023 Bean NW, Ibrahim JG, Psioda MA.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
An exploration of childhood antecedents of female adult malaise in two British birth cohorts: Combining Bayesian model averaging and recursive partitioning [PDF]
We use information from two prospective British birth cohort studies to explore the antecedents of adult malaise, an indicator of incipient depression. These studies include a wealth of information on childhood circumstances, behaviour, test scores and ...
John Hobcraft, Wendy Sigle-Rushton
core
Forecasting Pathogen Dynamics with Bayesian Model-Averaging: Application to Xylella fastidiosa. [PDF]
Bull Math Biol, 2023 Abboud C +3 more
europepmc +1 more source