Results 61 to 70 of about 343,435 (310)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Predictive RANS simulations via Bayesian Model-Scenario Averaging [PDF]
, 2014 The turbulence closure model is the dominant source of error in most Reynolds-Averaged Navier–Stokes simulations, yet no reliable estimators for this error component currently exist.
CINNELLA, Paola
core +1 more source
Mathematics, 2023 In this paper, we propose a model averaging estimation for the varying-coefficient partially linear models with missing responses. Within this context, we construct a HRCp weight choice criterion that exhibits asymptotic optimality under certain ...
Jie Zeng, Weihu Cheng, Guozhi Hu
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Detrending the Waveforms of Steady-State Vowels
Entropy, 2020 Steady-state vowels are vowels that are uttered with a momentarily fixed vocal tract configuration and with steady vibration of the vocal folds. In this steady-state, the vowel waveform appears as a quasi-periodic string of elementary units called pitch ...
Marnix Van Soom, Bart de Boer
doaj +1 more source
On the Average Random Probing Model
IACR Transactions on Cryptographic Hardware and Embedded SystemsMasking is one of the main countermeasures against side-channel analysis since it relies on provable security. In this context, “provable” means that a security bound can be exhibited for the masked implementation through a theoretical analysis in a given threat model. The main goal in this line of research is therefore to provide the tightest security
Julien Béguinot, Loïc Masure
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An analogue model of phase-averaging procedures [PDF]
Journal of Econometrics, 1987 This paper considers the statistical and econometric effect that fixed n-period phase-averaging has on time series generated by some simple dynamic processes. We focus on the variance and autocorrelation of the data series and of the disturbance term for levels and difference equations involving the phase-average data. Further, we examine the effect of
Julia Campos +2 more
openaire +5 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Demographic Research, 2013 Background: Population forecasts are widely used for public policy purposes. Methods to quantify the uncertainty in forecasts tend to ignore model uncertainty and to be based on a single model.
Guy J. Abel +5 more
doaj +1 more source