Results 71 to 80 of about 343,435 (310)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Incorporating Digital Footprints into Credit-Scoring Models through Model Averaging
MathematicsDigital footprints provide crucial insights into individuals’ behaviors and preferences. Their role in credit scoring is becoming increasingly significant.
Linhui Wang +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Equivalence between volume averaging and moments matching techniques for mass transport models in porous media. [PDF]
, 2010 This paper deals with local non-equilibrium models for mass transport in dual-phase and dual-region porous media. The first contribution of this study is to formally prove that the time-asymptotic moments matching method applied to two-equation models is
Davit, Yohan +5 more
core +1 more source
Regression models for average hazard
BiometricsAbstract Limitations of using the traditional Cox’s hazard ratio for summarizing the magnitude of the treatment effect on time-to-event outcomes have been widely discussed, and alternative measures that do not have such limitations are gaining attention.
Hajime Uno +4 more
openaire +2 more sources
Benchmark priors for Bayesian model averaging [PDF]
Journal of Econometrics, 2001 In contrast to a posterior analysis given a particular sampling model, posterior model probabilities in the context of model uncertainty are typically rather sensitive to the specification of the prior. In particular, 'diffuse' priors on model-specific parameters can lead to quite unexpected consequences.
Carmen Fernández +2 more
openaire +5 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Macroeconomic forecasting using model averaging
, 2009 PhDRecently, there has been a broadening concern on forecasting techniques that are applied on large data sets, since economists in business and management want to deal with the great magnitude of information. In this analysis, the issue of forecasting
Verra, Christina
core
Model Selection and Model Averaging
, 2021 In Chaps. 4 and 5 we explored Maximum Likelihood estimation and Bayesian statistics and, given a particular model, used our data to estimate the unknown parameter θ. The validity of the model itself was not questioned, except for a brief detour into the Bayes factor.
Göran Kauermann +2 more
openaire +1 more source