BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Aerospace aluminum surface defect detection method based on Multi-Scale Convolution and attention mechanism. [PDF]
Zhang R, Cai S, He Z, Zhao Y.
europepmc +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
EDAER: Entropy-Driven Approach for Entity and Relation Extraction in Chinese Cyber Threat Intelligence. [PDF]
Li Y +6 more
europepmc +1 more source
Computational insights into the natural phage endolysin linker landscape. [PDF]
Cremelie E +3 more
europepmc +1 more source
Machine learning-based prediction of 30-day unplanned readmission risk in day surgery lung cancer patients after lobectomy or sublobectomy: a real-world study. [PDF]
Han N +9 more
europepmc +1 more source
When Do Generics Feel Justifiable? A Registered Report Bridging Key Theories. [PDF]
Hermans F +3 more
europepmc +1 more source
Multi-Evidence Clinical Reasoning With Retrieval-Augmented Generation for Emergency Triage: Retrospective Evaluation Study. [PDF]
Wong HS, Wong TK.
europepmc +1 more source

