Results 71 to 80 of about 1,178,337 (307)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Linguistic Representation of Emotions in Japanese and Hungarian: Quantity and Abstractness
In the present paper, two linguistic aspects of emotion expression are studied in the form they are performed in present day Japanese and Hungarian. After a brief summary on the recent emotional researches connected to Japanese culture and language, the
Márton SZEMEREY
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Sheafifiable homotopy model categories, II
[For part I, cf. \textit{T. Beke}, Math. Proc. Camb. Philos. Soc. 129, No. 3, 447-475 (2000; Zbl 0964.55018)]. Suppose one has a category \({\mathcal C}\) and a functor \(F\) from \({\mathcal C}\) to \({\mathcal S}\)\textit{ets}. Then there is an induced functor from the category \(s{\mathcal C}\) of simplicial objects in \({\mathcal C}\) to simplicial
openaire +3 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Discreteness and completeness for $Θ_n$-models of $(\infty,n)$-categories [PDF]
Julia E. Bergner
openalex +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source

