Results 41 to 50 of about 171,654 (251)
Counterexample-Preserving Reduction for Symbolic Model Checking
Journal of Applied Mathematics, 2014 The cost of LTL model checking is highly sensitive to the length of the formula under verification. We observe that, under some specific conditions, the input LTL formula can be reduced to an easier-to-handle one before model checking. In such reduction,
Wanwei Liu +5 more
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On the Complexity of ATL and ATL* Module Checking [PDF]
Electronic Proceedings in Theoretical Computer Science, 2017 Module checking has been introduced in late 1990s to verify open systems, i.e., systems whose behavior depends on the continuous interaction with the environment.
Laura Bozzelli, Aniello Murano
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Consistency checking of UML business model
Technological and Economic Development of Economy, 2011 Unified modelling language (UML) is often used in practice for modelling business system (BS) by various aspects. UML model of business system consists of different aspect models and their usage for information system (IS) design is related with ...
Olegas Vasilecas +2 more
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Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Bounded saturation-based CTL model checking; pp. 59–70 [PDF]
Proceedings of the Estonian Academy of Sciences, 2013 Formal verification is becoming a fundamental step of safety-critical and model-based software development. As part of the verification process, model checking is one of the current advanced techniques to analyse the behaviour of a system. Symbolic model
András Vörös +2 more
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Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Model checking of trusted cryptographic module
Tongxin xuebao, 2010 The formal security analysis was given for the trusted cryptographic module according to the specification of the trusted cryptographic module using model checking tools. The flaws in the AP protocol were pointed and the solution was given.
CHEN Xiao-feng, FENG Deng-guo
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source