Results 61 to 70 of about 21,783,491 (356)

Stateless model checking for TSO and PSO [PDF]

open access: yesActa Informatica, 2015
We present a technique for efficient stateless model checking of programs that execute under the relaxed memory models TSO and PSO. The basis for our technique is a novel representation of executions under TSO and PSO, called chronological traces ...
P. Abdulla   +5 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Model Checking CSL for Markov Population Models [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
Markov population models (MPMs) are a widely used modelling formalism in the area of computational biology and related areas. The semantics of a MPM is an infinite-state continuous-time Markov chain.
David Spieler   +2 more
doaj   +1 more source

Formal Verification of STPA with Model Checking

open access: yesScientific Journal of Gdynia Maritime University, 2023
As technology advances, hardware-centric systems are rapidly moving towards software-centric ones, and their complexity is rapidly increasing. In particular, systems directly related to safety require thorough verification.
Ryeonggu Kwon, Gihwon Kwon
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Model Checking Based Approach for Compliance Checking

open access: yesInformation Technology And Control, 2019
Process mining is the set of techniques to retrieve a process model starting from available logging data. The discovered process model has to be analyzed to verify it respects the defined properties, i.e., the so-called compliance checking. Our aim is to use a model checking based approach to verify compliance. First, we propose an
Martinelli F.   +5 more
openaire   +6 more sources

Adaptive Model Checking [PDF]

open access: yesLogic Journal of IGPL, 2002
We consider the case where inconsistencies are present between a system and its corresponding model, used for automatic verification. Such inconsistencies can be the result of modeling errors or recent modifications of the system. Despite such discrepancies we can still attempt to perform automatic verification.
Doron Peled   +2 more
openaire   +2 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Model Checking Spatial Logics for Closure Spaces [PDF]

open access: yesLogical Methods in Computer Science, 2017
Spatial aspects of computation are becoming increasingly relevant in Computer Science, especially in the field of collective adaptive systems and when dealing with systems distributed in physical space. Traditional formal verification techniques are well
Vincenzo Ciancia   +3 more
doaj   +1 more source

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