Results 61 to 70 of about 23,407,383 (367)

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül   +2 more
wiley   +1 more source

Counterexample-Preserving Reduction for Symbolic Model Checking

open access: yesJournal of Applied Mathematics, 2014
The cost of LTL model checking is highly sensitive to the length of the formula under verification. We observe that, under some specific conditions, the input LTL formula can be reduced to an easier-to-handle one before model checking. In such reduction,
Wanwei Liu   +5 more
doaj   +1 more source

On the Complexity of ATL and ATL* Module Checking [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2017
Module checking has been introduced in late 1990s to verify open systems, i.e., systems whose behavior depends on the continuous interaction with the environment.
Laura Bozzelli, Aniello Murano
doaj   +1 more source

Lazy Probabilistic Model Checking without Determinisation [PDF]

open access: yes, 2015
The bottleneck in the quantitative analysis of Markov chains and Markov decision processes against specifications given in LTL or as some form of nondeterministic B\"uchi automata is the inclusion of a determinisation step of the automaton under ...
Hahn, Ernst Moritz   +4 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Consistency checking of UML business model

open access: yesTechnological and Economic Development of Economy, 2011
Unified modelling language (UML) is often used in practice for modelling business system (BS) by various aspects. UML model of business system consists of different aspect models and their usage for information system (IS) design is related with ...
Olegas Vasilecas   +2 more
doaj   +1 more source

Complexity of ITL model checking: some well-behaved fragments of the interval logic HS

open access: yes, 2015
Model checking has been successfully used in many computer science fields, including artificial intelligence, theoretical computer science, and databases.
Molinari, A., Montanari, A., Peron, A.
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Bounded saturation-based CTL model checking; pp. 59–70 [PDF]

open access: yesProceedings of the Estonian Academy of Sciences, 2013
Formal verification is becoming a fundamental step of safety-critical and model-based software development. As part of the verification process, model checking is one of the current advanced techniques to analyse the behaviour of a system. Symbolic model
András Vörös   +2 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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