Results 81 to 90 of about 221,743 (312)

Symbolic Model Checking of Dual Transition Petri Nets

open access: yes, 2002
This paper describes the formal verification of the recently introduced Dual Transition Petri Net (DTPN) models [12], using model checking techniques.
Varea, Mauricio   +9 more
core   +1 more source

Continuous Verification of Large Embedded Software using SMT-Based Bounded Model Checking [PDF]

open access: yes, 2010
The complexity of software in embedded systems has increased significantly over the last years so that software verification now plays an important role in ensuring the overall product quality.
Cordeiro, Lucas   +8 more
core   +1 more source

Learning Markov Decision Processes for Model Checking [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2012
Constructing an accurate system model for formal model verification can be both resource demanding and time-consuming. To alleviate this shortcoming, algorithms have been proposed for automatically learning system models based on observed system ...
Hua Mao   +5 more
doaj   +1 more source

Graphical and numerical diagnostic tools to assess multiple imputation models by posterior predictive checking

open access: yesHeliyon, 2023
Problem: The congenial of the imputation model is crucial for valid statistical inferences. Hence, it is important to develop methodologies for diagnosing imputation models.
Mingyang Cai   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Teaching Model Checking to Undergraduates

open access: yesStudia Universitatis Babes-Bolyai: Series Informatica, 2010
The way program verification is taught in our faculty is firstly described. One of the verification methods is model checking, shortly presented to the students in one lecture. One laboratory project consists in using the SPIN tool.
Andreea Vescan, Militon Frentiu
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Model Checking Spatial Logics for Closure Spaces [PDF]

open access: yesLogical Methods in Computer Science, 2017
Spatial aspects of computation are becoming increasingly relevant in Computer Science, especially in the field of collective adaptive systems and when dealing with systems distributed in physical space. Traditional formal verification techniques are well
Vincenzo Ciancia   +3 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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