Results 81 to 90 of about 21,783,491 (356)

Rich Counter-Examples for Temporal-Epistemic Logic Model Checking [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2012
Model checking verifies that a model of a system satisfies a given property, and otherwise produces a counter-example explaining the violation. The verified properties are formally expressed in temporal logics.
Simon Busard, Charles Pecheur
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

On the Power of Statistical Model Checking [PDF]

open access: yes, 2016
This paper contains material for our tutorial presented at STRESS 2016. This includes an introduction to Statistical Model Checking algorithms and their rare event extensions, as well as an introduction to two well-known SMC tools: Plasma and Uppaal.
Larsen, Kim Guldstrand, Legay, Axel
openaire   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Optimization Procedures in Affine Model Checking

open access: yesМоделирование и анализ информационных систем, 2011
Symbolic model checking is based on a compact representation of sets of states and transition relations. At present there are three basic approaches of symbolic model checking: BDD-methods, bounded model checking using SAT-solvers, and various algebraic ...
N. O. Garanina
doaj  

Hardware Model Checking Algorithms and Techniques

open access: yesAlgorithms
Digital systems are nowadays ubiquitous and often comprise an extremely high level of complexity. Guaranteeing the correct behavior of such systems has become an ever more pressing need for manufacturers.
Gianpiero Cabodi   +3 more
doaj   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Probabilistic and Hybrid Model Checking Deployments for Wireless Sensor Networks [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2012
In the early stages of system development, model checking is a good practice for examining the WSNs (Wireless Sensor Networks). Model checking involves verifying a system\'s properties based on the system\'s finite state model. For varying applications
Mohsin Memon   +2 more
doaj  

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