Results 151 to 160 of about 84,423 (301)

Functional Mini-Elbow Joint

open access: yes, 2010
Half-scale plastic replica which approximates natural joint motions and delineates their articular surfaces with blue color-coding. Includes the distal half of the humerus articulated with the proximal halves of the radius and ulna.

core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A Critique of the Authoritative Source of Truth Concept in Model-Based Systems Engineering

open access: yes
693697With the ongoing adoption of Model-Based Systems Engineering (MBSE) as a best practice in several domains there are ongoing efforts to improve the maturity of MBSE methods. In the vision for MBSE several organizations and actors foresee a landscape
Zimmermann, Thomas, Cederbladh, Johan
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

PAC-Companion Structure Using Dynamic Cash Reserve

open access: yes, 2008
This paper presents a model for optimally designing a collateralized mortgage obligation (CMO) with a planned amortization class (PAC)-companion structure using dynamic cash reserve.
Da-shan Huang A   +3 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Conflict Resolution in Model Versioning

open access: yes, 2010
Optimistic version control systems enable globally distributed teams of developers to work together asynchronously. Every developer works on a local copy and consequently, no developer is ever detracted from working by waiting for a resource.
Kaufmann, Petra   +2 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Model-Driven Approach for Automatic Model Information Aggregation in Structured Documents

open access: yes
403413While models are widely used in software development projects originating from industry and academic research, their documentation can be a time-intensive process.
Strey, Lukas, Henzgen, Arne
core   +1 more source

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