Results 171 to 180 of about 84,423 (301)

Reply: Generative AI-Powered Virtual Assistant for Guideline-Directed Medical Therapy Optimization. [PDF]

JACC Adv
Navarese EP, Leader JH, Koolaji S, Kereiakes DJ, Gorog DA.   +4 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Partial mycoheterotrophy in the arbuscular mycorrhizal Gentiana squarrosa (Gentianaceae) demonstrated by coculture assays using C₃ and C₄ plants. [PDF]

Mycorrhiza
Yamato M, Sasuga M, Shimabukuro K, Kusakabe R, Suetsugu K.   +4 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A digital twin approach for transforming prescription drug labeling. [PDF]

Front Pharmacol
Kimko H, Kimko E, Venkatapurapu SP.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Navigating a vulnerable transition: a qualitative study of the role of companions and providers in pregnancy and childbirth in Burkina Faso. [PDF]

BMJ Open
Wallengren E, Ouedraogo K, Hanson C, Mölsted Alvesson H, Bocoum FY, Kaboré CP, Dumont A, Betrán AP, Cleeve A.   +8 more
europepmc   +1 more source

UC-248 Campus AI Companion Mobile App [PDF]

The Campus AI Companion app is designed to enhance students\u27 university experiences by providing personalized recommendations for courses, events, clubs, and career paths.
Takou, Aurelien, Koodjo, Manuella, Taponzing Donfack, Dorian, Sokoudjou Gatsing, Leopold, Djoumessi, Yann   +4 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Association between cesarean section and labor companion in pregnant women giving birth: A prospective cohort study at Hung Vuong hospital, Vietnam. [PDF]

Eur J Midwifery
Vo TM, Minh Ngo TT, Nguyen NH, Tran DV, Nguyen DQ, Nguyen HM, Hoang TTA.   +6 more
europepmc   +1 more source