Results 201 to 210 of about 69,583 (261)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Tutorial on Analyzing Paired Longitudinal Data With Serial Correlation and Making Comparisons Between Groups, With Examples for Opioid Consumption and Quality of Life. [PDF]

Anesth Analg
Dexter F, Mueller RN, Bartels K.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Tracking spread of carbapenemase-producing Enterobacterales between humans and companion animals: successes and challenges. [PDF]

Front Cell Infect Microbiol
Dietrich JM, Vagnone PMS, Dale JL, Beaudoin AL, Ruhland A, Kollmann L, Cole SD.   +6 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Constructing targeted minimum loss/maximum likelihood estimators: a simple illustration to build intuition. [PDF]

Am J Epidemiol
Ross RK, Montoya LM, Goin DE, Díaz I, Renson A.   +4 more
europepmc   +1 more source

Decoding ferroptosis in intracerebral hemorrhage: multidimensional monitoring and integrative perspectives beyond single biomarkers. [PDF]

Front Neurol
Xiao C, Deng M, Zhang D.
europepmc   +1 more source

PsittaWel: A welfare assessment tool for companion parrots. [PDF]

Anim Welf
Piseddu A, van Zeeland Y, Hemsworth L, Rault JL.   +3 more
europepmc   +1 more source

Clinical factors, service type, and clinical outcomes associated with canine parvovirus in dogs presented at the KNUST Veterinary Teaching Hospital in Kumasi, Ghana. [PDF]

Companion Anim Health Genet
Agbota JD, Folitse RD, Opoku ED, Kodie DO, Tasiame W, Emikpe BO.   +5 more
europepmc   +1 more source