Results 131 to 140 of about 2,267,483 (329)
Finite Element Analysis of Adaptability of Completion String and Wellbore Curvature
Shiyou jixie, 2017 The sidetracked short-radius horizontal well applied in high build up rate section of wells in Suizhong 36-1 oilfield leads to the outstanding adaptability issue of completion string and wellbore.To address the issue,the completion string of a well in ...
Xu Jie +5 more
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Mathematical model bounds for maximizing the minimum completion time problem
Journal of Applied Mathematics and Computational Mechanics, 2021 Mahdi Jemmali, Abdullah Alourani
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Deep Temporal Reasoning in Video Language Models: A Cross-Linguistic Evaluation of Action Duration and Completion through Perfect Times [PDF]
Olga Loginova, Sofía Ortega Loguinova
openalex +1 more source
Model Completeness for Rational Trees
Abstract We analyze the theory of rational trees with finitely many constructors, infinitely many atoms and an atomicity predicate. We design a new decision procedure, proving in addition that this theory is model-complete. We also show that the enrichment of the language with selectors and simultaneous parametric fixpoints enjoys quantifier ...
Silvio Ghilardi, Lia M. Poidomani
openaire +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
The Impact of Early Colleges on Postsecondary Performance and Completion
AERA OpenEarly colleges are a model of schooling that combines the high school and college experiences, providing students the opportunity to simultaneously earn a high school diploma and an associate degree or 2 years of college credit.
Julie A. Edmunds +4 more
doaj +1 more source