Results 111 to 120 of about 226,838 (267)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Population Risk Improvement with Model Compression: An Information-Theoretic Approach. [PDF]

Entropy (Basel), 2021
Bu Y, Gao W, Zou S, Veeravalli VV.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Research on Rapid Detection of Underwater Targets Based on Global Differential Model Compression

Journal of Marine Science and Engineering
Large-scale deep learning algorithms have emerged as the primary technology for underwater target detection, demonstrating exceptional inference effectiveness and accuracy.
Weishan Li, Yilin Li, Ruixue Li, Haozhe Shen, Wenjun Li, Keqiang Yue   +5 more
doaj   +1 more source

Autonomous Binarized Focal Loss Enhanced Model Compression Design Using Tensor Train Decomposition. [PDF]

Micromachines (Basel), 2022
Liu M, Luo S, Han K, DeMara RF, Bai Y.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Wireless Network Optimization for Federated Learning with Model Compression in Hybrid VLC/RF Systems. [PDF]

Entropy (Basel), 2021
Huang W, Yang Y, Chen M, Liu C, Feng C, Poor HV.   +5 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Multi-Faceted Adaptive Token Pruning for Efficient Remote Sensing Image Segmentation

Remote Sensing
Global context information is essential for semantic segmentation of remote sensing (RS) images. Due to their remarkable capability to capture global context information and model long-range dependencies, vision transformers have demonstrated great ...
Chuge Zhang, Jian Yao
doaj   +1 more source

A Novel Deep-Learning Model Compression Based on Filter-Stripe Group Pruning and Its IoT Application. [PDF]

Sensors (Basel), 2022
Zhao M, Tong X, Wu W, Wang Z, Zhou B, Huang X.   +5 more
europepmc   +1 more source