Results 91 to 100 of about 15,583,552 (309)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
DOES YOUR EVENT LOG FIT THE HIGH-LEVEL PROCESS MODEL?
Моделирование и анализ информационных систем, 2015 Process mining is a relatively new field of computer science, which deals with process discovery and analysis based on event logs. In this paper we consider the problem of models and event logs conformance checking.
A. K. Begicheva, I. A. Lomazova
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Strategic fit: model development and fitness analysis of a manufacturing unit
Production and Manufacturing Research: An Open Access Journal, 2019 Though Bangladesh is one of the largest garments manufacturing country in the world and there happened revolutionary changes more than four decades ago, they couldn’t achieve sustainable platform yet.
Md. Habibur Rahman, Azizur Rahman
doaj +1 more source
Efficient algorithm for testing goodness-of-fit for classification of high dimensional data
Lietuvos Matematikos Rinkinys, 2009 Let us have a sample satisfying d-dimensional Gaussian mixture model (d is supposed to be large). The problem of classification of the sample is considered. Because of large dimension it is natural to project the sample to k-dimensional (k = 1, 2, . . .)
Gintautas Jakimauskas
doaj +1 more source
Model-fitting in the presence of outliers [PDF]
2011 IEEE International Symposium on Information Theory Proceedings, 2011 We study the problem of parametric model-fitting in a finite alphabet setting. We characterize the weak convergence of the goodness-of-fit statistic with respect to an exponential family when the observations are drawn from some alternate distribution. We then study the effects of outliers on the model-fitting procedure by specializing our results to ∈-
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
“Argh! The World Doesn't Fit the Model!”
Media TheoryThis article examines how data annotation in news organizations serves as a site of friction and world-making, shaping how AI systems categorize and interpret journalism.
Nanna Bonde Thylstrup +1 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source