Results 81 to 90 of about 15,583,552 (309)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Testing a Best-Fit Hydrodynamical Model Using PCA

open access: yesProceedings, 2019
Recently, a comprehensive Bayesian analysis was performed to simultaneously extract the values of a number of hydrodynamic parameters necessary for compatibility with a limited set of experimental data from the LHC.
Tiago Nunes da Silva   +6 more
doaj   +1 more source

Measures of relative model fit

open access: yesComputational Statistics & Data Analysis, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Department of Statistics, University of Florida Griffin-Floyd Hall, Gainesville, FL, USA ( host institution )   +2 more
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Predicting Measurement Model Misfit With Machine Learning While Accounting for Nuisance Parameters – An Illustration

open access: yesPsychological Test Adaptation and Development
: Developing valid measurement models for latent variables, such as personality traits, is essential for accurate psychological assessment. A critical aspect of this process is evaluating the fit of psychometric models.
David Goretzko, Melanie Viola Partsch
doaj   +1 more source

Distribution free goodness-of-fit tests for linear processes [PDF]

open access: yes, 2004
This article proposes a class of goodness-of-fit tests for the autocorrelation function of a time series process, including those exhibiting long-range dependence.
Velasco Gómez, Carlos   +8 more
core   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Analysis of Model Fit and Test Information on Otis-Lennon School Ability Test Using Item Response Theory

open access: yesJPAIR
The Otis-Lennon School Ability Test (OLSAT) is widely used in different academic institutions for various purposes, such as admission tests, performance predictions, and intelligence tests.
Rey-Mark Basagre
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy