Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
The Validation of the Persian Version of Sugar Addiction Questionnaire: Factor Structure, Item Analysis and Model Fit. [PDF]
Iran J PsychiatryAlavi SS +10 more
europepmc +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Point-of-care CAR T manufacturing solutions: can 1 model fit all? [PDF]
Blood AdvUrbano-Ispizua Á, Shah NN, Kekre N.
europepmc +1 more source
Melanocytic Skin Tumors: Does the Molecular Progression Model Fit With the Routine Clinicopathological Practice? [PDF]
Dermatol Pract Concept, 2020 Ferrara G, Bradamante M.
europepmc +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Semi-Empirical Approach to Evaluating Model Fit for Sea Clutter Returns: Focusing on Future Measurements in the Adriatic Sea. [PDF]
Entropy (Basel)Vondra B.
europepmc +1 more source
"How Well Does Your Structural Equation Model Fit Your Data?": Is Marcoulides and Yuan's Equivalence Test the Answer? [PDF]
CBE Life Sci Educ, 2020 Peugh J, Feldon DF.
europepmc +1 more source
Fit of Isolation by Distance Models: Curve Fitting [PDF]
Human Heredity, 1988 openaire +2 more sources
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source