Results 71 to 80 of about 2,644,305 (305)

Structuring the European Administrative Space - Channels of EU Penetration and Mechanisms ofNational Change [PDF]

The author provides an analytical model to capture mechanisms of supranational impact on national public administrations. The aim is to understand how we can perceive a European administrative space given the persistent diversity between member states ...
Eva G. Heidbreder
core  

Teaching Population Health: Innovations in the integration of the healthcare and public health systems [PDF]

, 2018
Population health is a critical concept in healthcare delivery today. Many healthcare administrators are struggling to adapt their organization from fee-for-service to value delivery.
Carmalt, Julie H., Caron, Rosemary M., Hewitt, Anne M., Hooker, Edmond A.   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Enhancing the efficiency of local government in the context of reducing the administrative expenditures [PDF]

The concerns on enhancing the efficiency of public administration, in particular the local government, are moreover present in the concerns of local authorities and specialised literature.
Matei, Ani, Savulescu, Carmen
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

From Theory to Practice: Enhancing Public Administration Leaders’ Capacities Through Collaborative Training Programs

Transylvanian Review of Administrative Sciences
Education and training of public leaders are critical for public administration performance and achieving the Sustainable Development Goals (SDGs). Public leaders act as a bridge between political power and public administration, serving as catalysts for
David Ferraz
doaj   +1 more source

INTEGRATED GOVERNANCE – A REAL STRATEGIC OPTION FOR AN EFFECTIVE ROMANIAN LOCAL PUBLIC ADMINISTRATION [PDF]

Based on the fact that governance is referring to the processes of governing which includes all public management organizations, the paper contains some opinions of the specialists concerning governance and integrated governance concept.
Armenia ANDRONICEANU
core  

Modernizace veřejné správy (analýza strategického tahu) [PDF]

, 2006
Referát analyzuje problém modernizace veřejné správy a její inovační trendy v ČR. Rozlišuje mezi tzv. nabídkovým modelem veřejné správy (úředně-správního,resp. samosprávního systému) a tzv. poptávkovým systémem orientovaným na občana jako klienta veřejné
Ochrana, František
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Modern governments: in search of a relevant model of the public administration system

RUDN Journal of Public Administration
The rapid changes in the modern world raise questions about the ability of national governments to manage them in the face of local and global turbulence.
Rashid T. Mukhaev
doaj   +1 more source