Conspecificity of the model organism Ulva mutabilis and Ulva compressa (Ulvophyceae, Chlorophyta)
As one of the most abundant and ubiquitous representatives of marine and brackish coastal macrophytobenthos communities, the genus Ulva is not only an important primary producer but also of ecological and morphogenetic interest to many scientists.
S. Steinhagen +3 more
semanticscholar +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Dynamical strategies for obstacle avoidance during Dictyostelium discoideum aggregation: a Multi-agent system model [PDF]
Chemotaxis, the movement of an organism in response to chemical stimuli, is a typical feature of many microbiological systems. In particular, the social amoeba \textit{Disctyostelium discoideum} is widely used as a model organism, but it is not still ...
Maggiora, Marco, Proverbio, Daniele
core +1 more source
Linking Supply Chain Disruption Orientation to Supply Chain Resilience and Market Performance with the Stimulus–Organism–Response Model [PDF]
Aaron Rae Stephens +2 more
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Living cells are made up of individual parts, i.e. the genome, the proteins, the RNA and lipid molecules as well as the metabolites and ions. However, life depends on the functional interaction among these components which is often organized in networks.
Bingyao Zhu, J. Stülke
semanticscholar +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
The Influence of a Hospitable Healthcare Environment on Patient Emotions and Behavioral Responses [PDF]
A structural model is proposed and empirically examined that investigates the influence of a medical center’s environment on patient responses. A stimulus-organism-response (S-O-R) model, often used to frame hospitality service research, is adapted ...
Mody, Makarand, Suess, Courtney
core
pathDIP 4: an extended pathway annotations and enrichment analysis resource for human, model organisms and domesticated species [PDF]
Sara Rahmati +8 more
openalex +1 more source
Genetic architecture of dispersal behaviour in the post-harvest pest and model organism Tribolium castaneum [PDF]
Michael D. Pointer +4 more
openalex +1 more source

