Results 101 to 110 of about 23,341,870 (343)

Conspecificity of the model organism Ulva mutabilis and Ulva compressa (Ulvophyceae, Chlorophyta)

open access: yesJournal of Phycology, 2018
As one of the most abundant and ubiquitous representatives of marine and brackish coastal macrophytobenthos communities, the genus Ulva is not only an important primary producer but also of ecological and morphogenetic interest to many scientists.
S. Steinhagen   +3 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Dynamical strategies for obstacle avoidance during Dictyostelium discoideum aggregation: a Multi-agent system model [PDF]

open access: yes, 2019
Chemotaxis, the movement of an organism in response to chemical stimuli, is a typical feature of many microbiological systems. In particular, the social amoeba \textit{Disctyostelium discoideum} is widely used as a model organism, but it is not still ...
Maggiora, Marco, Proverbio, Daniele
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

SubtiWiki in 2018: from genes and proteins to functional network annotation of the model organism Bacillus subtilis

open access: yesNucleic Acids Res., 2017
Living cells are made up of individual parts, i.e. the genome, the proteins, the RNA and lipid molecules as well as the metabolites and ions. However, life depends on the functional interaction among these components which is often organized in networks.
Bingyao Zhu, J. Stülke
semanticscholar   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

The Influence of a Hospitable Healthcare Environment on Patient Emotions and Behavioral Responses [PDF]

open access: yes, 2018
A structural model is proposed and empirically examined that investigates the influence of a medical center’s environment on patient responses. A stimulus-organism-response (S-O-R) model, often used to frame hospitality service research, is adapted ...
Mody, Makarand, Suess, Courtney
core  

pathDIP 4: an extended pathway annotations and enrichment analysis resource for human, model organisms and domesticated species [PDF]

open access: gold, 2019
Sara Rahmati   +8 more
openalex   +1 more source

Genetic architecture of dispersal behaviour in the post-harvest pest and model organism Tribolium castaneum [PDF]

open access: hybrid, 2023
Michael D. Pointer   +4 more
openalex   +1 more source

Home - About - Disclaimer - Privacy