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Caenorhabditis elegans, as an emerging model organism, has been widely used in multiple disciplines such as medicine, life science, and environmental science in recent years, due to its characteristics of short life cycle, clear genetic background ...
LI Zhuo+4 more
doaj +1 more source
Microfluidic Devices in Advanced Caenorhabditis elegans Research
The study of model organisms is very important in view of their potential for application to human therapeutic uses. One such model organism is the nematode worm, Caenorhabditis elegans. As a nematode, C.
Muniesh Muthaiyan Shanmugam+1 more
doaj +1 more source
In vivo detection of lamellocytes in Drosophila melanogaster. [PDF]
Drosophila has recently become a powerful model organism for studies of innate immunity. The cellular elements of innate immunity in Drosophila, the hemocytes, have been characterized by morphological criteria, molecular markers, and cell-type-specific ...
Brand+17 more
core +1 more source
Towards the Model Driven Organization [PDF]
Todays modern organization is faced with a need for rapid response to changes from external business pressures by updating systems and operational procedures. The effect of such continuous evolution eventually leads to sub- optimal configurations of its underlying systems.
Clark, Tony+5 more
openaire +4 more sources
Bear management changes management actions according to the horizontal axis of the population size and the vertical axis of the number of nuisance bears. Aiming for the target population size of Ntar, Actions I and II protect the bears, and Action IV reduces the population.
Hiroyuki Matsuda+5 more
wiley +1 more source
Summary: Syringomyelia is a common clinical lesion associated with cerebrospinal fluid flow abnormalities. By a reversible model with chronic extradural compression to mimic human canalicular syringomyelia, we explored the spatiotemporal pathological ...
Chunli Lu+6 more
doaj +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Mitochondrial Quality Control in Alzheimer’s Disease: Insights from Caenorhabditis elegans Models
Alzheimer’s disease (AD) is a complex neurodegenerative disorder that is classically defined by the extracellular deposition of senile plaques rich in amyloid-beta (Aβ) protein and the intracellular accumulation of neurofibrillary tangles (NFTs) that are
Upasana Ganguly+3 more
doaj +1 more source
Model Organisms are Not (Theoretical) Models [PDF]
AbstractMany biological investigations are organized around a small group of species, often referred to as ‘model organisms’, such as the fruit fly Drosophila melanogaster.
Levy, Arnon, Currie, Adrian
openaire +3 more sources
The amyloid world hypothesis of the origin‐of‐life posits that the first functional polymers on the early Earth were structurally stable cross‐β‐sheet‐based peptide amyloids capable of Darwinian‐like evolution. Peptide amyloids display self‐replication and information transfer, as well as catalytic, adaptive, and evolutive properties.
Carl Peter J. Maury
wiley +1 more source