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Model organisms — A historical perspective
Journal of Proteomics, 2010Much of our knowledge on heredity, development, physiology and the underlying cellular and molecular processes is derived from the studies of model, or reference, organisms. Despite the great variety of life, a common base of shared principles could be extracted by studying a few life forms, selected based on their amenability to experimental studies ...
Müller, B, Grossniklaus, U
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Recursive self-organizing network models
Neural Networks, 2004Self-organizing models constitute valuable tools for data visualization, clustering, and data mining. Here, we focus on extensions of basic vector-based models by recursive computation in such a way that sequential and tree-structured data can be processed directly.
B. HAMMER +3 more
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A Universal Organic Solvation Model.
The Journal of Organic Chemistry, 1996Thepartitioningofamoleculebetweentwophaseshasinnumerableconsequencesinchemistry;forexample,thepartitioning between air and neat liquid determinesvaporpressure(Henry’slaw),thepartitioningbetweenaqueousbiophasesandlipidbilayersiscriticaltodrugdelivery ...
, Giesen, , Gu, , Cramer, , Truhlar
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Journal of Experimental Psychology: Learning, Memory, and Cognition, 1993
Previous research (Radvansky & Zacks, 1991) has shown that the fan effect is mediated not by the number of nominal associations paired with a concept but by the number of mental models into which related concepts are organized. Specifically, newly learned "facts" about different objects in one location are integrated into a single mental model and no ...
G A, Radvansky, D H, Spieler, R T, Zacks
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Previous research (Radvansky & Zacks, 1991) has shown that the fan effect is mediated not by the number of nominal associations paired with a concept but by the number of mental models into which related concepts are organized. Specifically, newly learned "facts" about different objects in one location are integrated into a single mental model and no ...
G A, Radvansky, D H, Spieler, R T, Zacks
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Nature Reviews Genetics, 2003
Nineteenth-century biology embraced the complexity and variety of living things. In the twenty-first century, biologists have returned to these attributes of life with functional and comparative genomics. We could not have done so without the intense study of 'genetically domesticated' model organisms in the twentieth century.
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Nineteenth-century biology embraced the complexity and variety of living things. In the twenty-first century, biologists have returned to these attributes of life with functional and comparative genomics. We could not have done so without the intense study of 'genetically domesticated' model organisms in the twentieth century.
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The Model Organism Dictyostelium discoideum
2013Much of our knowledge of molecular cellular functions is based on studies with a few number of model organisms that were established during the last 50 years. The social amoeba Dictyostelium discoideum is one such model, and has been particularly useful for the study of cell motility, chemotaxis, phagocytosis, endocytic vesicle traffic, cell adhesion ...
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Integrating non-mammalian model organisms in the diagnosis of rare genetic diseases in humans
Nature Reviews Genetics, 2023Shinya Yamamoto +2 more
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