Results 141 to 150 of about 2,691,356 (263)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Achieving Occam's razor: Deep learning for optimal model reduction. [PDF]

PLoS Comput Biol
Antal BB, Chesebro AG, Strey HH, Mujica-Parodi LR, Weistuch C.   +4 more
europepmc   +1 more source

Parallel Tempering with Lasso for model reduction in systems biology. [PDF]

PLoS Comput Biol, 2020
Gupta S, Lee REC, Faeder JR.
europepmc   +1 more source

Railway model reduction

, 2006
Technical report for the collaboration between ISTI and ALstom Transport s.p.a. (Identification of a subset of a Statecharts model and Rules).
openaire   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Effective Model Reduction Scheme for the Electronic Structure of Highly Doped Semiconducting Polymers. [PDF]

J Chem Theory Comput
Prodhan S, Troisi A.
europepmc   +1 more source

Model reduction by mean-field homogenization in viscoelastic composites. I. Primal theory. [PDF]

Proc Math Phys Eng Sci, 2020
Idiart MI, Lahellec N, Suquet P.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A new model reduction method based PBC control for grid-connected inverter with LCL-filter. [PDF]

Sci Rep
Gao C, Tan F.
europepmc   +1 more source

Model reduction by mean-field homogenization in viscoelastic composites. II. Application to rigidly reinforced solids. [PDF]

Proc Math Phys Eng Sci, 2020
Idiart MI, Lahellec N, Suquet P.
europepmc   +1 more source