Results 51 to 60 of about 3,167,714 (312)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Combined Reduction [PDF]

open access: yes, 2014
presented at Model Reduction and Approximation for Complex Systems - june ...
Ohlberger, Mario   +5 more
core   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Dynamic Maximum Entropy Reduction

open access: yesEntropy, 2019
Any physical system can be regarded on different levels of description varying by how detailed the description is. We propose a method called Dynamic MaxEnt (DynMaxEnt) that provides a passage from the more detailed evolution equations to equations for ...
Václav Klika   +3 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Balanced Realization and Model Order Reduction for Nonlinear Systems Based on Singular Value Analysis [PDF]

open access: yes, 2004
This paper discusses balanced realization and model order reduction for both continuous-time and discrete-time general nonlinear systems based on singular value analysis of the corresponding Hankel operators.
Fujimoto, Kenji   +6 more
core   +1 more source

Total Suspended Particle Emissions Modelling in an Industrial Boiler

open access: yesEnergies, 2018
Particulate matter emission into the atmosphere is a massive-scale problem. Fossil fuel combustion is an important source of this kind of pollution. The knowledge of total suspended particle (TSP) emissions is the first step for TSP control.
Guillermo Ronquillo-Lomeli   +4 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Summer monsoon precipitation patterns and their relationship to flood probabilities across Pakistan

open access: yesJournal of Hydrology: Regional Studies
Study region: In Pakistan, the climate crisis manifests most dangerously through extreme monsoon precipitation and subsequent flooding. Study focus: To quantify the relationship between summer monsoon precipitation and flood probability, the study ...
Mohib Ullah   +5 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy