Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Corrigendum to "Design and analysis of UPQC in a microgrid using model reference adaptive control ensemble with back-stepping controller" [Heliyon Volume 10, Issue 14, July 2024, Article e34140]. [PDF]
Das SK +8 more
europepmc +1 more source
Position control of redundant manipulators using an adaptive error-based control scheme [PDF]
A Cartesian-space control scheme is developed to control the motion of kinematically redundant manipulators with 7 degrees of freedom (DOF). The control scheme consists mainly of proportional derivative (PD) controllers whose gains are adjusted by an ...
Nguyen, Charles C., Zhou, Zhen-Lei
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Modelling and Neuro-Adaptive Robust Control Algorithms for Solid Fuel Rockets
This study presents the development of a methodology for designing neuro-adaptive robust controllers based on a reference model associated with an artificial neural network of radial basis functions (ANN-RBF) for solid fuel suborbital rockets.
Christian Danner Ramos de Carvalho +1 more
doaj
Design and analysis of UPQC in a microgrid using model reference adaptive control ensemble with back-stepping controller. [PDF]
Das SK +8 more
europepmc +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Experimental studies on model reference adaptive control with integral action employing a rotary encoder and tachometer sensors. [PDF]
Wu GQ, Wu SN, Bai YG, Liu L.
europepmc +1 more source

