Results 101 to 110 of about 1,893,219 (314)
The Structure of Evolutionary Model Space for Proteins across the Tree of Life. [PDF]
Biology (Basel), 2023 Scolaro GE, Braun EL.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Dynamic Modeling of Crew Performance for Long-Duration Space Missions [PDF]
, 2005 Crew time is one of the most valuable and limited resources during long-duration space missions. Crew time requirements fluctuate depending on variations in crew performance.
Both, A. J. +7 more
core +2 more sources
Finding excesses in model parameter space
European Physical Journal C: Particles and FieldsSimulation-based inference (SBI) makes it possible to infer the parameters of a model from high-dimensional low-level features of the observed events. In this work we show how this method can be used to establish the presence of a weak signal on top of ...
Kierthika Chathirathas +3 more
doaj +1 more source
Model‐Space Localization in Serial Ensemble Filters
Journal of Advances in Modeling Earth Systems, 2019 Ensemble‐based data assimilation systems typically use covariance localization to dampen spurious correlations associated with sampling error while increasing the rank of the covariance estimate. Variational methods use model‐space localization, in which
Anna Shlyaeva +2 more
doaj +1 more source
Effect of model space priors on statistical inference with model uncertainty. [PDF]
N Engl J Stat Data Sci, 2023 Porwal A, Raftery AE.
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Theoretical growth model space for Cities [PDF]
, 2012 This work raises a theoretical model of spatial growth for the cities in which makes explicit that the growth of population and income growth determined the city s expansion in terms of area built for business and the area destined for housing At the ...
Dr. Jos Reyes Bernal BellAn
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Model for Assessment of Public Space Quality in Town Centers [PDF]
, 2016 Public space is an important element of urban structure, playing various spatial, social and economic roles in towns/cities. Its quality influences the quality of life of the inhabitants and the attractiveness of the town as a whole. Public space located
Wojnarowska, Anna
core +1 more source