Results 111 to 120 of about 1,893,219 (314)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Identification and data-driven model reduction of state-space representations of lossless and dissipative systems from noise-free data [PDF]

open access: yes, 2011
We illustrate procedures to identify a state-space representation of a lossless- or dissipative system from a given noise-free trajectory; important special cases are passive- and bounded-real systems.
Trentelman, Harry   +9 more
core   +1 more source

Evaluation of commercial space accessibility in tourist town: A case research of Maotai Town in China

open access: yesFrontiers of Architectural Research
Accessibility is a crucial indicator for evaluating the spatial rationalization of commercial facilities in an area, impacting both commercial development and service efficiency. The objective of this research is to analyze the commercial space layout of
Lai Xu   +4 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Modeling and Resolving Uncertainty in DIKWP Model

open access: yesApplied Sciences
The paper examines the various uncertainties encountered in high-frequency trading (HFT) environments and delves into the multiple challenges faced by HFT firms in navigating the Dodd–Frank Wall Street Reform and Consumer Protection Act (referred to as ...
Kunguang Wu, Yucong Duan
doaj   +1 more source

MODELING SEARCH PROCESSES IN SPACE

open access: yesPapers in Regional Science, 1991
The paper extends the well-known economic search model to take into account the fact that all search takes place in two-dimensional space. This adds arouting problem to thestopping problem usually discussed in the search literature. The paper shows that these two problems are interdependent and can only be solved simultaneously. This relates thespatial
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A function space model for canonical systems [PDF]

open access: yes, 2011
Recently, a generalization to the Pontryagin space setting of the notion of canonical (Hamiltonian) systems which involves a finite number of inner singularities has been given.
Woracek, H., Langer, Matthias
core  

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