The Characterization Pattern of Overburden Deformation with Distributed Optical Fiber Sensing: An Analogue Model Test and Extensional Analysis. [PDF]
Sensors (Basel), 2020 Yuan Q, Chai J, Ren Y, Liu Y.
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A structural equation model test of affect, family warmth, and substance use among American Indian reservation-based adolescents. [PDF]
Psychol Addict BehavSwaim RC, Crabtree MA, Egli MR.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Study on the Ratio and Model Test of Similar Materials of Heavily Weathered Granite. [PDF]
Materials (Basel)Hu G, Song W, Yu X, Lin M, Tie Y, He B.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Model test study on the mechanical response of the deep buried tunnel lining. [PDF]
Sci RepDuan L, Feng J, Song J, Yao S.
europepmc +1 more source
A Model Test for the Influence of Lateral Pressure on Vertical Bearing Characteristics in Pile Jacking Process Based on Optical Sensors. [PDF]
Sensors (Basel), 2020 Wang Y, Liu X, Sang S, Zhang M, Wang P.
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Model test study of bridge pile horizontal bearing behavior under landslide deformation. [PDF]
Sci RepZhao YY, Fu HY, Yang T, Zhou MZ, Li H.
europepmc +1 more source