Results 101 to 110 of about 35,180,990 (360)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
International Journal of Modern Physics A, 1992 Random matrix models based on an integral over supermatrices are proposed as a natural extension of bosonic matrix models. The subtle nature of superspace integration allows these models to have very different properties from the analogous bosonic models. Two choices of integration slice are investigated. One leads to a perturbative structure which is
openaire +2 more sources
Modeling Lamellar Cracks. [PDF]
, 2013 In this work, studies of models simulating lamellar cracks were conducted. These cracks are formed in rolled sheets with non-metallic inclusions. Studies of lamellar cracks began in the 1960s, but there is still no satisfactory theory explaining their ...
Jaroniek, Mieczysław +1 more
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Protein Structure Modeling with MODELLER
, 2014 Genome sequencing projects have resulted in a rapid increase in the number of known protein sequences. In contrast, only about one-hundredth of these sequences have been characterized at atomic resolution using experimental structure determination methods.
Webb, Benjamin, Sali, Andrej
openaire +6 more sources
Understanding covariate shift in model performance [version 3; referees: 2 approved]
F1000Research, 2016 Three (3) different methods (logistic regression, covariate shift and k-NN) were applied to five (5) internal datasets and one (1) external, publically available dataset where covariate shift existed.
Georgia McGaughey +2 more
doaj +1 more source
WORD-FORMATION MODELING. [PDF]
, 2012 The study of the ways in which new complex words are built on the basis of other words or morphemes is known as word-formation. The search for appropriate alternatives that may be found in morphological variants or in case of usage phrase structures is ...
Чумак, Л. М.
core
Lifelong Sequential Modeling with Personalized Memorization for User Response Prediction
, 2019 User response prediction, which models the user preference w.r.t. the presented items, plays a key role in online services. With two-decade rapid development, nowadays the cumulated user behavior sequences on mature Internet service platforms have become
Bian, Weijie +10 more
core +1 more source