Results 111 to 120 of about 6,742,242 (297)
Nature Communications, 2019 Soft porous crystals hold big promise as functional nanoporous materials due to their stimuli responsive flexibility. Here, molecular dynamics simulations reveal a new type of spatial disorder in mesoscale crystals that helps to understand the size ...
Sven M. J. Rogge +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Global atmospheric distribution of microplastics with evidence of low oceanic emissions
npj Climate and Atmospheric ScienceRecent investigations based on sea–air transfer physical mechanistic studies suggest that the global ocean’s contribution to atmospheric microplastic emissions is significantly lower (four orders of magnitude) than previously estimated.
Shanye Yang +4 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Developing a service-oriented component framework for a landscape modeling language [PDF]
, 2009 With modeling and simulation, it is possible to study how a system works before trying to predict how it would behave in a variety of situations. However, when modeling landscape processes, issues related to space, time and multiple scales need to be ...
Ait Lahcen, Ayoub +3 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
MolPROP: Molecular Property prediction with multimodal language and graph fusion
Journal of CheminformaticsPretrained deep learning models self-supervised on large datasets of language, image, and graph representations are often fine-tuned on downstream tasks and have demonstrated remarkable adaptability in a variety of applications including chatbots ...
Zachary A. Rollins +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 1999 Excerpt: A cognitive process in which individuals change response patterns through imagining themselves engaging in the desired responses rather than by observing another person model the responses.
Bufford, Rodger K.
core
In vitro and in vivo stability of a highly efficient long-acting cocaine hydrolase
Scientific ReportsIt is recognized as a promising therapeutic strategy for cocaine use disorder to develop an efficient enzyme which can rapidly convert cocaine to physiologically inactive metabolites.
Linyue Shang +9 more
doaj +1 more source