Results 231 to 240 of about 35,180,990 (360)

Numerical Forecasting with the Barotropic Model [PDF]

, 1955
Bert Bolin
openalex   +1 more source

Modeling of species distributions with Maxent: new extensions and a comprehensive evaluation

, 2008
Steven J. Phillips, Miroslav Dudík
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Micro-Expression Recognition via LoRA-Enhanced DinoV2 and Interactive Spatio-Temporal Modeling. [PDF]

Sensors (Basel)
Wang M, Tang X, Wang B, Ren J.
europepmc   +1 more source

Grassland management and nitrate leaching, a model approach [PDF]

, 2001
Th.V. Vellinga, A.H.J. van der Putten, M. Mooij   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Habitat-Based Predictions of Bridle Shiner (<i>Notropis bifrenatus</i>) in the Northeastern United States. [PDF]

Ecol Evol
Katz LS, Coghlan SM, Carpenter MA, Kinnison MT, Zydlewski JD.   +4 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Application of FT-NIR spectroscopy to the prediction of Chromium contamination in soil by evolutionary chemometrics. [PDF]

PLoS One
Hong S, Liang Z, Chen H, Weng J, Cai K, Wu X.   +5 more
europepmc   +1 more source

Parenting behaviors in mice: Olfactory mechanisms and features in models of autism spectrum disorders

Ana Dudas, Thiago S. Nakahara, Lucie P. Pellissier, Pablo Chamero   +3 more
openalex   +1 more source