Results 61 to 70 of about 425,473 (267)

Improved bounds of Mitrinović–Adamović-type inequalities by using two-parameter functions

open access: yesJournal of Inequalities and Applications, 2023
This paper provides improved bounds of inequalities of Mitrinović–Adamović type by using two-parameter functions. It achieves a much better approximation effect than those bounds of prevailing methods. A new method based on the Páde interpolation is used
Guiping Qian, Xiao-Diao Chen
doaj   +1 more source

COMPLEX, MODEL, SYSTEM

open access: yesEuropean Science Review, 2022
The article discusses artificial, natural systems and complexes. Natural systems cannot be such, because, by definition, a system is a set of elements and relationships between them. Unlike artificial systems, in natural systems it is often impossible to establish such sets.
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Fine-Grained Classification via Hierarchical Bilinear Pooling With Aggregated Slack Mask

open access: yesIEEE Access, 2019
Extracting discriminative fine-grained features is essential for fine-grained image recognition tasks. Many researchers utilize expensive human annotations to learn discriminative part models, which may be impossible for real-world applications. Recently,
Min Tan   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Towards Sophisticated Air Traffic Control System Using Formal Methods

open access: yesModelling and Simulation in Engineering, 2018
We propose a general formal modeling and verification of the air traffic control system (ATC). This study is based on the International Civil Aviation Organization (ICAO), Federal Aviation Administration (FAA), and National Aeronautics and Space ...
Abdessamad Jarrar, Youssef Balouki
doaj   +1 more source

Characteristics of Co-Allocated Online Services and Batch Jobs in Internet Data Centers: A Case Study From Alibaba Cloud

open access: yesIEEE Access, 2019
In order to reduce power and energy costs, giant cloud providers now mix online and batch jobs on the same cluster. Although the co-allocation of such jobs improves machine utilization, it challenges the data center scheduler and workload assignment in ...
Congfeng Jiang   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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