Results 31 to 40 of about 82,657 (256)
Statistical modeling and forecasting are very important for decision-making in any field of life. This paper has two major objectives, namely, statistical modeling and forecasting of real phenomena. For covering the first aim (i.e., statistical modeling),
Lai Ting +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
AbstractThe creation and use of models in science is of great importance for knowledge production and communication. For example, toy models are often used as idealized explanatory models in physics education. Models can be a powerful tool for exploring phenomena in ways that facilitate learning.
Sebastian Kilde Löfgren +2 more
openaire +1 more source
Competences of contemporary surveyor [PDF]
- utilization of contemporary methods, methodologies, techniques and technology for measuring and surveying of terrain, objects and geospatial phenomena, - evidence, registration, management, administration and valuation of real estate, - designing ...
Bashkim IDRIZI
doaj
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
This study introduces a novel family of generalized stochastic neural network (GSNN) operators with enhanced modeling and approximation capabilities.
Abeer Aljohani
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Real-Time Acoustic Phenomena Modelling for Computer Games Audio Engine
Abstract This article presents an efficient method of modelling acoustic phenomena for real-time applications such as computer games. Simplified models of reflections, transmission, and medium attenuation are described along with assessments conducted by a professional sound designer.
Bartłomiej MIGA, Bartosz ZIÓŁKO
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

