Results 31 to 40 of about 82,657 (256)

Analysis of bitcoin prices using a heavy-tailed version of Dagum distribution and machine learning methods

open access: yesAlexandria Engineering Journal, 2023
Statistical modeling and forecasting are very important for decision-making in any field of life. This paper has two major objectives, namely, statistical modeling and forecasting of real phenomena. For covering the first aim (i.e., statistical modeling),
Lai Ting   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Rolling balls or trapping ions? How students relate models to real‐world phenomena in the physics laboratory

open access: yesScience Education, 2023
AbstractThe creation and use of models in science is of great importance for knowledge production and communication. For example, toy models are often used as idealized explanatory models in physics education. Models can be a powerful tool for exploring phenomena in ways that facilitate learning.
Sebastian Kilde Löfgren   +2 more
openaire   +1 more source

Competences of contemporary surveyor [PDF]

open access: yesMicro, Macro & Mezzo Geoinformation, 2018
- utilization of contemporary methods, methodologies, techniques and technology for measuring and surveying of terrain, objects and geospatial phenomena, - evidence, registration, management, administration and valuation of real estate, - designing ...
Bashkim IDRIZI
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A novel family of generalized stochastic neural network operators with illustrations of their various capabilities

open access: yesAin Shams Engineering Journal
This study introduces a novel family of generalized stochastic neural network (GSNN) operators with enhanced modeling and approximation capabilities.
Abeer Aljohani
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Real-Time Acoustic Phenomena Modelling for Computer Games Audio Engine

open access: yesArchives of Acoustics, 2015
Abstract This article presents an efficient method of modelling acoustic phenomena for real-time applications such as computer games. Simplified models of reflections, transmission, and medium attenuation are described along with assessments conducted by a professional sound designer.
Bartłomiej MIGA, Bartosz ZIÓŁKO
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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