Results 51 to 60 of about 82,657 (256)

Modeling and Simulation in Engineering Design and Technology: Improving Project/Product Performance

International Journal of Technology, 2014
The use of modeling and simulation (M&S) to increase project or product performance within engineering design and technology is well recognized. The reasons for increasing the use of modeling and simulation applications include the ability to simulate ...
Mohammed Ali Berawi
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

BRANCHING PROCESS MODELLING: A TOOL FOR DECIPHERING COMPLEX REAL-WORLD PHENOMENA USING R PROGRAMMING

FUDMA JOURNAL OF SCIENCES, 2023
The reproduction of organisms such as human beings, cells or neutrons can be modeled via branching processes.The theory of branching processes offers suitable mathematical models to depict the chance-based progression of systems, where elements like cells, particles, or general individuals replicate and perish over a certain lifespan.
openaire   +1 more source

Experimental validation of the model approach in professional psychological selection of law enforcement officers

Психология и право, 2018
This article discusses the problems of modeling personality-suitability of employees of internal affairs agencies (staff) in the psychology of performance. The model is presented as an activity centred construct. Subject of study modeled in stages in the
Kubyshko V.L., Kruk V.M., Noss I.N., Borodina T.I.   +3 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Information theory and possible mathematical descriptions of economical and social systems based on real physical phenomena

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2019
Recent approaches in informatics to model large complex systems are considered following the ideas from real phenomena explained by physical tools. The econophysics and sociophysics are considered.
M. Gaeta, G. Iovane, A. Makarenko
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

On certain surface integrals related to the conormal derivative problem

Partial Differential Equations in Applied Mathematics
The non-homogeneous conormal derivative problems for nonlinear, second-order divergence form elliptic equations with singular data appear naturally in mathematical modeling of real phenomena involving problems of image recovery, the thermistor problem ...
Dian K. Palagachev
doaj   +1 more source

Cognitive aggregate-flow metamodel of the process automatic spacecraft flight control

Вестник Самарского государственного технического университета. Серия: Технические науки, 2020
Currently, there is an urgent scientific problem of ensuring the effective implementation of the automatic spacecraft (AS) flight program, taking into account the material, energy and information resource limitations of onboard systems (OS).
Vladimir S. Kovtun
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source