Results 61 to 70 of about 96,250 (257)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

On certain surface integrals related to the conormal derivative problem

Partial Differential Equations in Applied Mathematics
The non-homogeneous conormal derivative problems for nonlinear, second-order divergence form elliptic equations with singular data appear naturally in mathematical modeling of real phenomena involving problems of image recovery, the thermistor problem ...
Dian K. Palagachev
doaj   +1 more source

Cognitive aggregate-flow metamodel of the process automatic spacecraft flight control

Вестник Самарского государственного технического университета. Серия: Технические науки, 2020
Currently, there is an urgent scientific problem of ensuring the effective implementation of the automatic spacecraft (AS) flight program, taking into account the material, energy and information resource limitations of onboard systems (OS).
Vladimir S. Kovtun
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Pleasure, Imagination, Fear and Joy: Applied Themes in Nicole Oresme’s de Configurationibus [PDF]

Memoirs of the Scientific Sections of the Romanian Academy, 2018
The present work explores the idea that concepts present in Nicole Oresme’s work, and rooted in the medieval revival of Corpus Aristotelicum, are reflected throughout active areas of research today.
Isabel M. Serrano, Bogdan D. Suceavă, Anael Verdugo   +2 more
doaj  

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Scientific Inference with Interpretable Machine Learning: Analyzing Models to Learn About Real-World Phenomena

Minds and Machines
AbstractTo learn about real world phenomena, scientists have traditionally used models with clearly interpretable elements. However, modern machine learning (ML) models, while powerful predictors, lack this direct elementwise interpretability (e.g. neural network weights).
Timo Freiesleben, Gunnar König, Christoph Molnar, Álvaro Tejero-Cantero   +3 more
openaire   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Nonlinear modeling of the mechanical properties of materials in CAD systems: from experiment to simulation

Budownictwo o Zoptymalizowanym Potencjale Energetycznym
The article investigates the potential application of CAD systems for predicting the mechanical properties of structural materials by comparing experimental test results with data from nonlinear simulations.
Olena Gumen, Mykhailo Vterkovskyi, Nadiia Tykholaz, Adam Ujma   +3 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source