Results 151 to 160 of about 259,378 (315)
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Journal of Emergency Practice and Trauma, 2015 Introduction: Emergency department is the most important part of a hospital and it seems that 24-hour presence of emergency medicine specialist can be effective in improving the performance of this ward.
Mohammad Reza Amiresmaili +3 more
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Modeling services liberalization : the case of Kenya [PDF]
This paper employs a 55 sector small open economy computable general equilibrium model of the Kenyan economy to assess the impact of the liberalization of regulatory barriers against foreign and domestic business service providers in Kenya.
Balistreri, Edward J. +2 more
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Towards a re-engineering method for web services architectures [PDF]
, 2004 Recent developments in Web technologies – in particular through the Web services framework – have greatly enhanced the flexible and interoperable implementation of service-oriented software architectures.
Ronan Barrett +3 more
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Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Services liberalization in preferential trade arrangements : the case of Kenya [PDF]
Given the growing importance of commitments to foreign investors in services in regional trade agreements, it is important to develop applied general equilibrium models to assess the impacts of liberalization of barriers to multinational service ...
Balistreri , Edward J., Tarr, David G.
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem +17 more
wiley +1 more source
Web services integration on the fly [PDF]
, 2008 In a net-centric environment, data, tools and people operate in a distributed network. A key research question is whether a software framework can become so usable and intelligent that integration of web services can be done on-the-fly as self ...
Leong, Hoe Wai
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Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Journal of Health Management & Informatics, 2016 Introduction: Family physician plan in Iran was conducted to establish service referral system. Its urban step began in 2012 and it was supposed that the effectiveness is enhanced and the costs are reduced.
Mohammad Hossein Mehrolhassani +1 more
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