Results 131 to 140 of about 341,194 (266)

Can Predictive Modeling Tools Identify Patients at High Risk of Prolonged Opioid Use After ACL Reconstruction? [PDF]

Clin Orthop Relat Res, 2020
Anderson AB, Grazal CF, Balazs GC, Potter BK, Dickens JF, Forsberg JA.   +5 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Sequence modeling tools to decode the biosynthetic diversity of the human microbiome. [PDF]

mSystems
Dason MS, Corà D, Re A.
europepmc   +1 more source

A database for evaluating the InMAP, APEEP, and EASIUR reduced complexity air-quality modeling tools. [PDF]

Data Brief, 2020
Baker KR, Amend M, Penn S, Bankert J, Simon H, Chan E, Fann N, Zawacki M, Davidson K, Roman H.   +9 more
europepmc   +1 more source

Flood Modelling Tool

The risk of pluvial flooding is going to increase as climate change causes an increase in intense precipitation along with urbanisation leading to an increase in impermeable surfaces. In the last decade, cities such as Malmö and Copenhagen have already experienced severe pluvial flooding that has caused extensive damage.
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Towards a widespread adoption of metabolic modeling tools in biopharmaceutical industry: a process systems biology engineering perspective. [PDF]

NPJ Syst Biol Appl, 2020
Richelle A, David B, Demaegd D, Dewerchin M, Kinet R, Morreale A, Portela R, Zune Q, von Stosch M.   +8 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

An nf-core framework for the systematic comparison of alternative modeling tools: the multiple sequence alignment case study. [PDF]

NAR Genom Bioinform
Santus L, Espinosa-Carrasco J, Rauschning L, Mir-Pedrol J, Trujnara I, Vignoli A, Mansouri L, Baltzis A, Floden EW, Di Tommaso P, Garriga E, Gudyś A, Deorowicz S, Gilchrist C, Steinegger M, Notredame C.   +15 more
europepmc   +1 more source

CORR Insights®: Can Predictive Modeling Tools Identify Patients at High Risk of Prolonged Opioid Use After ACL Reconstruction? [PDF]

Clin Orthop Relat Res, 2020
Joyner PW.
europepmc   +1 more source