Results 131 to 140 of about 5,613,073 (287)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
MODELING OF ANIMATED SIMULATIONS BY MAXIMA PROGRAM TOOLS
Інформаційні технології і засоби навчання, 2015 The article deals with the methodical features in training of computer simulation of systems and processes using animation. In the article the importance of visibility of educational material that combines sensory and thinking sides of cognition is noted.
Nataliya O. Bugayets
doaj
Opening a debate on open-source modeling tools: Pouring fuel on fire versus extinguishing the flare of a healthy debate. [PDF]
CPT Pharmacometrics Syst Pharmacol, 2021 Rostami-Hodjegan A, Bois FY.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Combining cross-section images and modeling tools to create high-resolution root system hydraulic atlases in Zea mays. [PDF]
Plant Direct, 2021 Heymans A, Couvreur V, Lobet G.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Letter to the Editor: Can Predictive Modeling Tools Identify Patients at High Risk of Prolonged Opioid Use After ACL Reconstruction? [PDF]
Clin Orthop Relat Res, 2021 Wang Q, Zhu H.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Advanced Engineering Research, 2012 Features of the mathematical modeling of drilling tools modernized for drilling deep holes are studied. A mathematical model of drilling, questions of stability, and existence of the drilling process are considered.
Tatyana S. Onoyko +2 more
doaj