Results 91 to 100 of about 3,231,941 (243)

Measuring Process Modelling Success [PDF]

open access: yes, 2002
Process-modelling has seen widespread acceptance, par ticularly on large IT-enabled Business Process Reengineering projects. It is applied, as a process design and management technique, across all life-cycle phases of a system.
Bandara, Wasana   +2 more
core   +2 more sources

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Parsimonious Catchment and River Flow Modelling [PDF]

open access: yes, 2002
It is increasingly the case that models are being developed as “evolving” products rather than\ud one-off application tools, such that auditable modelling versus ad hoc treatment of models becomes a\ud pivotal issue.
Booij, M.J.   +4 more
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Conceptual modelling: framework, principles, and future research [PDF]

open access: yes, 2007
The conceptual modelling task in a simulation project is very important and yet is still generally regarded as more of an art than a science. The meaning and nature of conceptual modelling are discussed and a framework set out.
Brooks, R J
core  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Two Monte Carlo studies for latent class segmentation models [PDF]

open access: yes, 2007
Model assessment and comparison are essential aspects of statistical inference. The likelihood ratio test is one of the main instruments for model selection; however, this is not appropriate when the model under consideration contains random effects.
21st European Simulation and Modelling Conference   +1 more
core  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Modelling glueballs

open access: yes, 2016
Glueballs are predicted in various theoretical approaches of QCD (most notably lattice QCD), but their experimental verification is still missing. In the low-energy sector some promising candidate for the scalar glueball exist, and some (less clear ...
Giacosa, Francesco
core   +2 more sources

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy