Results 141 to 150 of about 27,648,855 (348)
, 2003 Transverse dunes appear in regions of mainly unidirectional wind and high sand availability. A dune model is extended to two dimensional calculation of the shear stress.
Herrmann, Hans J., Schwämmle, Veit
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Modelling Selective Catalytic Reduction (SCR) of NOx to N2 over Cu-SSZ-13 [PDF]
, 2018 Modelling Selective Catalytic Reduction (SCR) of NOx to N2 over Cu-SSZ-13 Reduction of NOx emissions from diesel engine exhaust is an environmental issue driven by increasingly stringent emission regulations.
Epling, William
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Decision makers\u27 experience of participatory dynamic simulation modelling: Methods for public health policy [PDF]
, 2018 Background: Systems science methods such as dynamic simulation modelling are well suited to address questions about public health policy as they consider the complexity, context and dynamic nature of system-wide behaviours.
Atkinson, Jo-An +4 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Akka as a tool for modelling and managing a smart grid system
Journal of Edge ComputingThe article addresses big data processing challenges, fault tolerance, and consumer interaction in a smart grid network management system. It analyses the use of Akka for agent-based modelling of smart grid systems, which enables the creation of ...
Mykola Yaroshynskyi +4 more
doaj +1 more source