Results 221 to 230 of about 10,618,209 (336)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Model-guided geospatial surveillance system for antimalarial drug resistance. [PDF]

PLOS Glob Public Health
Gupta A, Harrison LE, Nain M, Phulgenda SS, Chhajed R, Kumar RS, Das A, Rahi M, Guerin PJ, Anvikar AR, Dhorda M, Flegg JA, Bharti PK.   +12 more
europepmc   +1 more source

Investigation of key contributors of CO2 emissions in extended STIRPAT model for newly industrialized countries: A dynamic common correlated estimator (DCCE) approach

, 2019
Ahmad Ghazali, Ghulam Ali
openalex   +1 more source

Development and Analysis of Artificial Neural Network Models for Rainfall Prediction by Using Time-Series Data [PDF]

, 2018
Neelam Mishra, Hemant Kumar Soni, Sanjiv Sharma, Arvind Kumar Upadhyay   +3 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Stability of Composite Plates with a Dense System of Ribs in Two Directions. [PDF]

Materials (Basel)
Marczak J, Rabenda M, Michalak B.
europepmc   +1 more source

Antarctica: modelling [PDF]

, 2004
Huybrechts, Philippe
core  

Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease

, 2011
María Ángeles Rosillo, Marina Sánchéz‐Hidalgo, Ana Cárdeno, Catalina Alarcón‐de‐la‐Lastra   +3 more
openalex   +2 more sources

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis [PDF]

, 2012
Rachel Tesla, Hamilton Parker Wolf, Pin Xu, Jordan Drawbridge, Sandi Jo Estill, Paula Huntington, Latisha McDaniel, Whitney Knobbe, Aaron Burket, Stephanie Tran, Ruth Starwalt, Lorraine Morlock, Jacinth Naidoo, Noelle S. Williams, Joseph M. Ready, Steven L. McKnight, Andrew A. Pieper   +16 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source